U.S. regulators have withdrawn their approval of a GSK Plc drug that the Trump administration had promoted as a treatment for autism, adding another twist to the unusual story of a decades-old drug.

The Food and Drug Administration is pulling its approval of Wellcovorin, a branded version of leucovorin from GSK Plc, according to a post Thursday...Read more

A small aircraft carrying two people crashed Thursday afternoon on Catalina Island, the Federal Aviation Administration confirmed.

The plane, a 2014 Airplane Factory Sling, took off from Zamperini Field in Torrance at 10:53 a.m. and was last seen at 11:13 a.m. near Avalon, per FlightAware.

The aircraft was en route to the island and crashed in...Read more

SACRAMENTO, Calif. — A Yolo County grand jury has made indictments for the July fireworks explosion in Esparto that killed seven people and ignited a 78-acre wildfire, the District Attorney’s Office announced Thursday.

At least three people connected to the Esparto fireworks explosion have been arrested. Sam Machado, a Yolo County Sheriff�...Read more

Federal immigration agents in Maryland used the state’s driver’s license database — without citing a traffic violation or outstanding warrant — to detain a driver in Howard County, a federal affidavit shows, raising legal and policy questions about how the information is used in immigration enforcement.

As part of “Operation Take Back...Read more

The outlook for Southern Nevada’s lifeline has only worsened as the Colorado River heads into runoff season.

Colorado Basin River Forecast Center hydrologist Cody Moser said in a webinar this week that if conditions persist as expected, it’s possible that runoff into Lake Powell could be under the lowest year on record, 2002, which is ...Read more

CHICAGO — The Rainbow PUSH Coalition has tapped the youngest son of the Rev. Jesse Jackson Sr. as its new leader, the organization said Thursday.

The announcement that Yusef Jackson would take over as the coalition’s president and CEO comes nearly two months after his father’s death reverberated across the country.

“I am deeply ...Read more

WASHINGTON — The Pentagon and the Vatican denied allegations of a rift following Pope Leo XIV’s criticism of the Trump administration and a news report of a contentious meeting between a papal envoy and a top U.S. defense official.

In separate statements, the two sides professed an eagerness to get along, saying the meeting that occurred in...Read more

LOS ANGELES — Twenty-one people are facing charges as part of a massive hospice fraud scheme that prosecutors say bilked California’s medical system out of $267 million.

Attorney General Rob Bonta on Thursday announced the results of an investigation called Operation Skip Trace. Five principal conspirators were arrested on suspicion of a ...Read more

Israel’s Prime Minister Benjamin Netanyahu agreed to hold talks with Lebanon as U.S. President Donald Trump said the Israeli leader is “going to low-key it” with strikes on the war-weary country, signaling some hope for deescalation.

Still, Netanyahu vowed to keep fighting Iran-backed Hezbollah in Lebanon, which on Wednesday suffered the ...Read more

Hunter Biden wants to fight either of President Donald Trump’s elder sons in a cage match.

The 56-year-old son of former President Joe Biden said it’s his understanding that popular YouTuber Andrew Callaghan is trying to put him in a ring with either Don Trump Jr. or Eric Trump.

Much the same way President Donald Trump routinely derides ...Read more

FORT LAUDERDALE, Fla. — After three hours inside the confines of the immigrant detention center in the Florida Everglades on Thursday, U.S. Rep. Debbie Wasserman Schultz said she discovered needlessly inhumane conditions, including 32 men housed in each cage, minimal food, and a persistent odor of urine.

“Everything about this screams ...Read more

LOS ANGELES — Los Angeles Mayor Karen Bass and City Council member Ysabel Jurado called Thursday for allotting more than $360 million to developers and nonprofits building and preserving affordable housing projects.

The appropriation, which requires City Council approval, would fund 80 projects, with construction of 1,528 new units and ...Read more

WASHINGTON — President Donald Trump will have wide latitude to keep his preferred pick leading the Justice Department after his firing of ally Pamela Bondi, including scenarios that could entirely avoid a Senate confirmation process well into the future.

Any permanent attorney general nominee could face a tough path to confirmation in the ...Read more

WASHINGTON — Pivotal negotiations in Pakistan this weekend between the United States and Iran could hinge on developments in Lebanon, where ongoing Israeli strikes Thursday risked derailing a wider regional ceasefire.

Tensions only deepened amid reports of limited Iranian drone attacks across the region, and as Arab states warned that the ...Read more

NEW YORK — Sgt. Erik Duran, the NYPD “Cooler Cop” who killed a fleeing drug-deal suspect in the Bronx by hurling a heavy, ice-filled cooler at him, got a three-to-nine-year prison sentence Thursday, drawing cheers from criminal justice reform advocates and vitriol from the former cop’s followers.

Duran, 38, wept as he stood before Judge...Read more

WASHINGTON — President Donald Trump said he was “optimistic” about a deal with Iran but later threatened Tehran over charging fees in the Strait of Hormuz, as Israeli strikes in Lebanon and the continued closure of the vital waterway jeopardized diplomatic talks.

“There are reports that Iran is charging fees to tankers going through the...Read more

CHICAGO — A lawyer for imprisoned House Speaker Michael Madigan told a federal appeals court on Thursday his conviction on an array of corruption counts should be overturned because there was no evidence that he agreed to enter into a bribery conspiracy with ComEd or took any specific official action on the utility’s behalf.

In the long-...Read more

NEW YORK — New York City Mayor Zohran Mamdani came into office on New Year’s Day with big plans, lots of enthusiasm and the mammoth challenge of putting his lofty campaign promises into action.

One hundred days later, the mayor has made headway on some of those campaign pledges, but he’s backpedaled or moderated his stance on others.

...Read more