SEATTLE — The Chicago White Sox had plenty of runners on base Thursday.

They just couldn’t get them in.

The Sox squandered several scoring chances, falling 4-3 to the Seattle Mariners in 11 innings in front of 37,930 at T-Mobile Park.

The Sox went 1 for 17 with runners in scoring position while being swept in the three-game series.

Dominic Canzone delivered the walk-off hit for the Mariners, driving in Eugenio Suárez with a single.

“It was a tough one,” Sox manager Will Venable said. “Credit the guys for battling. Pitching was outstanding. But a lot of things we can point to where we have to play better. Situational hitting wasn’t our best game there. Obviously execution on defense. Got to hold runners. There’s a good list of things we can just be better, we’ve got to be better.”

Michael A. Taylor and Brooks Baldwin homered in the loss. The team hit eight home runs in the series.

Baldwin’s homer in the seventh tied the score at 2. The Sox went ahead in the 10th when Lenyn Sosa scored on a wild pitch.

The Mariners tied it when Miles Mastrobuoni began the bottom of the 10th with a bunt. Third baseman Josh Rojas threw wildly to first, and Randy Arozarena scored the tying run.

Rojas had just entered as a defensive replacement.

“(Rojas is) a veteran, he’s a pro, he knows he has to make that play obviously,” Venable said. “That’s why he’s in there, to make those plays. We thought it was a defensive upgrade for us. It just didn’t work out.”

The Sox came up empty in the 11th. They left 12 runners on base for the game.

“We just have to continue to zone them up and make good swing decisions,” Venable said. “In the case of today, there was some situational stuff — runner on second (and) nobody out, runner on third (and) less than two (outs). We just have to think smaller, maybe, and do whatever we have to do to put the ball in play.”

Canzone ended it in the bottom of the 11th with a single to right. Suárez scored just ahead of Taylor’s throw from right field.

“We’ve just got to keep at it,” said starter Shane Smith, who allowed two runs on four hits and struck out eight in five sharp innings. “It’s not the first time we’ve lost like this. We went through this early on in the season.

“I think we’re in a better spot now than we were in April and May. Definitely well-equipped to handle it. Just go back and go get it tomorrow (against the Cleveland Guardians).”

Here are three takeaways from T-Mobile Park:

1. Chase Meidroth’s injured thumb ‘stalled out,’ leading to IL stint.

Meidroth felt “frustrated as heck” trying to push through a right thumb injury.

“It was not going as fast as I wanted it to, was doing everything to get it to come back as fast as possible,” Meidroth said Thursday morning. “It’s all right, take it day by day and give it a go next week.”

The Sox placed the second baseman/shortstop on the 10-day injured list Thursday with a right thumb bruise. The move is retroactive to Monday. Meidroth suffered the injury on July 30 against the Philadelphia Phillies when he was hit by a pitch. He has not had an at-bat since.

“He had an initial progress with the thumb feeling better,” Venable said. “Just kind of stalled out over the last couple of days. Just thought it was in his best interest and our best interest to give him a rest and get that thing healed up before we ask him to get back out there.”

Meidroth said it’s tough to hold a bat.

“Just swinging,” he said of the challenge. “Defense, it was uncomfortable, but I was able to play defense (entering in the ninth inning Sunday against the Los Angeles Angels). We were hoping it would speed up a little faster. It just kind of stayed pretty similar to last week.”

Venable said Meidroth “took a pretty good beating on that thumb.”

“Don’t swing for a couple of days, see if we can get it going even more and see where we’re at,” Venable said. “My guess though is he’ll come off when he’s eligible. But it’s going to be sore for a little bit. And just want to minimize the impact here, so give him a little more time.”

In Thursday’s corresponding move, the Sox selected the contract of infielder Jacob Amaya from Triple-A Charlotte. The Sox also designated pitcher Gus Varland for assignment.

2. Lenyn Sosa provided power during his hitting streak.

The infielder entered Wednesday with a career-high-tying eight-game hitting streak.

Sosa went hitless in his first three plate appearances before following a two-run home run from Mike Tauchman with one of his own in the seventh inning of the 8-6 loss.

It was the second straight day with a home run for Sosa. He hit a solo shot in the first inning of Tuesday’s 8-3 loss.

Before Wednesday’s game, Sosa said through an interpreter that the key has been “be ready for every pitch and don’t miss a pitch I can handle and do damage on.”

Sosa slashed .438/.500/.813 with four home runs and eight RBIs during the nine-game hitting streak, which ended after he went 0 for 4 on Thursday.

“Sosa can hit,” hitting coach Marcus Thames said before the game. “He’s been a guy that does his homework every single day, he’s prepared. Even (Wednesday) night, he was looking for a fastball, if you give me one, I’m going to hit it hard. Just him being prepared.”

Sosa went 14 for 32 during the streak.

“It’s no secret that your confidence level grows every time the results are good,” Sosa said. “No matter what, right now I’m just focused on don’t lose focus on the things I can control. Every pitch.”

3. Luis Robert Jr. reached a pair of milestones.

Robert hit the 100th home run of his career in the ninth inning Tuesday.

“It’s definitely special, it doesn’t matter where or what situation,” Robert said through an interpreter after the game. “Just to get 100 homers is always special.”

He reached another milestone Thursday, stealing second base in the eighth inning for the 100th of his career. Robert joined Minnie Miñoso, Ray Durham and Alexei Ramírez as the only players in Sox history to record at least 100 home runs and steals.

“When he stayed here post-(trade) deadline, it was kind of a sigh of relief with everybody because he is the heartbeat of our outfield, of our defense, of our lineup,” starter Davis Martin said of Robert on Tuesday. “He’s had some insane moments in a White Sox uniform and there’s a lot of respect for what he does on the field and what he brings to the table every day.”

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